Picture of a white rat in a researcher's gloved hand.
Ethics, Research

What is ethical animal research? A scientist and veterinarian explain

Federal research agencies follow guiding principles in evaluating the use and care of animals in research.These principles are summarized by the “3 R’s” of animal research: reduction, refinement and replacement. The 3 R’s encourage scientists to develop new techniques that allow them to replace animals with appropriate alternatives.

Immunology, Research, Transplantation

The journey to a pig-heart transplant began 60 years ago

On Friday, January 7 2022, David Bennett became the world’s first person to successfully receive a transplant of a pig’s heart. The eight-hour-long operation by surgeons at the University of Maryland Medical Center in Baltimore, USA, was no doubt arduous. But it was a short final step in a 60-year-long journey to genetically alter the pig’s heart so that it would not be immediately rejected – a journey that began with a plane crash in Oxford in the summer of 1940.