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Looking for Long Covid: A Clash of Definition and Study Design

Few experts dispute that long Covid can be debilitating, or that it warrants careful study. But in interviews with Undark, a number of experts said that it is misleading to frame long Covid as an increasing threat. The best data, they say, suggest that most people recover from the disorder and that long Covid rates will decline as people develop immunity.

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Electron micrograph of SARS-CoV-2, the coronavirus responsible for COVID-19

Three in five long COVID patients have organ damage a year after infection

From this first set of scans, we found 331 participants (62%) had organ damage. Impairment of the liver, pancreas, heart and kidneys were most common (affecting 29%, 20%, 19% and 15% of participants respectively). These 331 participants were followed up six months later with a further MRI scan.

We found that three in five of the original study participants (59%) had impairment in at least one organ a year after infection, while just over one in four (27%) had impairment in two or more organs. So, for the vast majority of participants who had organ damage at six months, it was sustained until at least 12 months.

While in some cases participants with organ damage were no longer experiencing symptoms, organ impairment was associated with a higher likelihood of persistent symptoms and reduced function at 12 months.

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woman sleeping on a sofa in a darkened room

Most long COVID cases had mild initial infections, UW study finds

Study found that a staggering 90% of people living with long COVID initially experienced only mild illness with COVID-19. After developing long COVID, however, the typical person experienced symptoms including fatigue, shortness of breath and cognitive problems such as brain fog – or a combination of these – that affected daily functioning. These symptoms had an impact on health as severe as the long-term effects of traumatic brain injury. Our study also found that women have twice the risk of men and four times the risk of children for developing long COVID.

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A computer-generated illustration of SARS-CoV-2, the coronavirus responsible for COVID-19.

Got Long Covid? Medical Expertise Is Vital, and Seniors Should Prepare to Go Slow

Older adults who have survived covid-19 are more likely than younger patients to have persistent symptoms such as fatigue, breathlessness, muscle aches, heart palpitations, headaches, joint pain, and difficulty with memory and concentration — problems linked to long covid. But it can be hard to distinguish lingering aftereffects of covid from conditions common in older adults such as lung disease, heart disease, and mild cognitive impairment.

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