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Coronavirus, COVID, Ethics, Research

Mixed Lessons from Intentionally Infecting People with Covid-19

The idea sounded counterintuitive, but by carefully dosing individuals with SARS-CoV-2 in a controlled setting, scientists could study how the virus affects the body and learn what factors may offer protective benefits.

These types of studies, called human challenge trials, could help fast-track understanding the deadly virus devastating the world, experts claimed. Others, though, questioned whether the potential benefits were worth the risk, particularly given the host of unknowns surrounding Covid-19, and the lack of available treatments at the time.

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Health News

Just two hours of exercise a week can bring you huge cardiovascular health benefits

A sedentary person who goes from doing nothing to exercising a couple of hours a week will see the greatest reductions in cardiovascular risk during this period. If they increase the amount they exercise to four hours a week, there would be additional – albeit smaller – reductions in risk (around 10%). But the benefits to cardiovascular health appear to max out after 4-6 hours a week – with no additional gains beyond this point for everyone.

A shot into a cup filled containing blue fentanyl-laced pills.
Addiction, Drugs, Fentanyl, Methamphetamine, Opioids

Stimulant Users Are Caught in Fatal ‘Fourth Wave’ of Opioid Epidemic

The first wave of the long-running and devastating opioid epidemic began in the United States with the abuse of prescription painkillers in the early 2000s. The second wave involved an increase in heroin use, starting around 2010. The third wave began when powerful synthetic opioids such as fentanyl started appearing in the supply around 2015. Now experts are observing a fourth phase of the deadly epidemic.

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Drugs, Mental Health, Research

Hallucinogens approved for treating psychiatric disorders: what does the science say?

Hallucinogens are now being presented as a breakthrough in the treatment of severe psychiatric disorders, such as depression or post-traumatic stress disorder, sometimes in combination with psychotherapy).

Despite being presented as innovations, the therapeutic potential of psychedelics is not a new discovery. In the 1960s and 70s, these substances were explored for medical use but quickly fell out of favour due to regulatory restrictions.

Now, in 2024, the question remains: Are psychedelics genuinely effective for treating psychiatric disorders?

Bmi weight obesity scale
Health News

Most adults will gain a pound this year – and every year. Here’s how to stop ‘weight creep’ Nick Fuller, University of Sydney As we enter a new year armed with resolutions to improve our lives, there’s a good chance we’ll…

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Aging, Brain and Nervous System, Dementia

A mouse study by researchers from the Allen Institute in Seattle provides roadmap for how aging may alter brain cell genetic activity.

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Pregnancy, Rural Health, Rural Hospitals, Women's Health

For Many Rural Women, Finding Maternity Care Outweighs Concerns About Abortion Access

A study that examined nearly 5,000 acute care hospitals found that by 2022, 52% of rural hospitals lacked obstetrics care after more than a decade of unit closures. The health implications of those closures for young women, the population most likely to need pregnancy care, and their babies can be significant. Research has shown that added distance between a patient and obstetric care increases the likelihood the baby will be admitted to a neonatal intensive care unit, or NICU.

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Diet, Health News, Nutrition, Prevention, Public Health

Junk food and drug use cut into life expectancy gains for states

Bad habits such as junk food, smoking and illicit drug use are preventing longer lifespans even as technology brings major progress in diseases such as cancer and heart disease, according to a new study by the Institute for Health Metrics and Evaluation at the University of Washington.

Nine of the 10 states (all but North Dakota) with the longest life expectancies for babies born this year are dominated by Democrats, and all 10 have expanded Medicaid under the Affordable Care Act. All 10 states with the shortest life expectancies are controlled by Republicans (though Kentucky has a Democratic governor), and they include five of the 10 states that have not expanded Medicaid.

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Drugs, Fitness, Weight Loss

Weight loss drugs help with fat loss – but they cause bone and muscle loss too

GLP-1-based drugs such as semaglutide (Wegovy) and tirzepatide (Mounjaro) work by helping people to feel less hungry. This results in them eating less – leading to weight loss.

Studies show that these drugs are very effective in helping people lose weight. In clinical trials of people with obesity, these drugs lead to a weight loss of up to 20% body weight in some instances.

But it’s important to note that not all the weight lost is fat. Research shows that up to one-third of this weight loss is so-called “non-fat mass” – this includes muscle and bone mass.