Claymation style illustration of a younger woman lifting small hand barbells
Drugs, Fitness, Weight Loss

Weight loss drugs help with fat loss – but they cause bone and muscle loss too

GLP-1-based drugs such as semaglutide (Wegovy) and tirzepatide (Mounjaro) work by helping people to feel less hungry. This results in them eating less – leading to weight loss.

Studies show that these drugs are very effective in helping people lose weight. In clinical trials of people with obesity, these drugs lead to a weight loss of up to 20% body weight in some instances.

But it’s important to note that not all the weight lost is fat. Research shows that up to one-third of this weight loss is so-called “non-fat mass” – this includes muscle and bone mass.

Walking in park
Aging, Fitness, Seniors

There’s a link between walking speed and ageing well. Here’s how you can improve your pace

Various studies have found a link between low walking speed in adults over 65 and a greater risk of cognitive impairment, cardiovascular disease, falls (which could lead to fractures), hospitalisation, and even an increased overall mortality rate.

A higher walking speed, on the other hand, is associated with increased functional capacity, meaning a better ability to move around and do activities independently. It is also linked to greater longevity.

But how fast should you walk?

Dall·e 2024 12 04 07.11.38 a claymation style illustration of an older man lifting weights in a cheerful and colorful home gym. the man is wearing a light workout outfit with sn
Aging, Fitness, Prevention, Seniors

Healthspan versus lifespan: The vital role of muscle in successful aging

The extension of life expectancy in the 20th century and beyond is one of humanity’s greatest achievements. However, it is crucial to draw a distinction between lifespan — the amount of time between birth and death — and healthspan, which is the amount of time during which a person is healthy within their lifespan. Older people are spending more time in poor health, and this represents a major individual and public health burden.

Illustration of a heavy-set man jogging in a city park.
Fitness, Genetics, Weight Loss

Your genetic profile may have a dominant effect on how well you lose weight through exercise. This might explain why two people who do an identical workout will see very different results.

Knee diagram.svg
Child Health, Fitness, Injury Prevention, Orthopedics

More children are getting ACL injuries – here’s what could be done to prevent them

One particularly nasty sporting injury is damage to the ACL – the anterior cruciate ligament in the knee, which attaches the thigh (femur) and shin (tibia) bones. ACL injuries have rocketed among children in England, and our research suggests that one cause of this is that children are not developing basic movement skills, such as jumping and hopping.