Aging, Brain and Nervous System, Drugs

What is delirium?

Up to one-third of older people admitted to hospital are diagnosed with delirium. This increases the risk of unnecessary functional decline, a longer hospital stay, falls, needing to be admitted to a residential aged care facility, and death. However, identifying the condition early reduces these risks. Delirium can also be prevented by identifying who is vulnerable to the condition and finding ways of reducing the person’s risk.

640px acl tear
Fitness, Musculoskeletal, Orthopedics, Surgery, Women's Health

Female football players are at much higher risk of career-ending ACL injuries – the science on why

Females have a wider pelvis relative to leg length, which results in increased angulation at the knee. The shape of the bones is also different in women in that the ACL passes through a narrower space to attach to the thigh bone, which may make it more susceptible to injury. The actual size of the ACL is also often smaller in females, so may be less able to withstand high forces.

Depressed girl mental health
Mental Health, Prevention, Social Determinants of Health

Mental Health Care Must Promote Wellness, Not Just Treat Illness

The nation’s mental health care system is currently focused almost exclusively on preventing and treating mental illness — conditions like depression, anxiety, and personality disorder that adversely affect a person’s mood and behavior. Although these are critical factors in mental health, so too are the components of life that are associated with feeling good, finding happiness and meaning, connecting with others, and feeling engaged — qualities that can be collectively described as positive mental health, or mental wellness.

Electron micrograph of SARS-CoV-2, the coronavirus responsible for COVID-19
Coronavirus, COVID, Infectious Disease

Three in five long COVID patients have organ damage a year after infection

From this first set of scans, we found 331 participants (62%) had organ damage. Impairment of the liver, pancreas, heart and kidneys were most common (affecting 29%, 20%, 19% and 15% of participants respectively). These 331 participants were followed up six months later with a further MRI scan.

We found that three in five of the original study participants (59%) had impairment in at least one organ a year after infection, while just over one in four (27%) had impairment in two or more organs. So, for the vast majority of participants who had organ damage at six months, it was sustained until at least 12 months.

While in some cases participants with organ damage were no longer experiencing symptoms, organ impairment was associated with a higher likelihood of persistent symptoms and reduced function at 12 months.

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Aging, Genetics, Social Determinants of Health

Epigenetic and social factors both predict aging and health – but new research suggests one might be stronger

For years, researchers have been using clinical factors normally collected at physicals, like hypertension, cholesterol and weight, as indicators to predict aging. The idea was that these measures could determine whether someone is a fast or slow ager at any point in their life cycle. But more recently, researchers have theorized that there are other biological markers that reflect aging at the molecular and cellular level. This includes modifications to a person’s genetic material itself, or epigenetics.